In recent years, the prevalence of fungal diseases has increased significantly. This is due to the active and not always competent use of cytostatics, antibiotics, corticosteroid hormones, the development of immunodeficiency states. In clinical practice, most often there is urogenital candidiasis, occurring in a chronic / acute form. Thrush is characterized by the presence of vesicles and point erosions, a lesion of the mucosa, which tends to crack and bleed in the vestibule, a purulent secretion of yellow / white, burning and itching in the perineum. Fluconazole for thrush is the drug of choice in systemic therapy of candidal infection. It is highly active in relation to Candida (only 3-6% of Candida strains are resistant to Fluconazole), has good bioavailability and a minimum of contraindications.
Fluconazole for thrush: how to take, instructions
Fluconazole is an antifungal drug of the triazole group. Fluconazole perfectly penetrates into urine, sputum, saliva, other tissue fluids. After oral intake, 90% of the drug enters the bloodstream, is excreted unchanged for 27-34 hours. It is produced in two forms: for oral (capsule) and intravenous (solution for injection) reception.
Indications for use:
- recurrent and acute urogenital candidiasis;
- generalized candidiasis; infections that affect the eyes, heart, respiratory and abdominal organs;
- Thrush mucous pharynx, digestive organs, oral cavity;
- cutaneous mycoses (fungal skin lesions in the groin, on the body, feet);
- as a prophylaxis for oncologists receiving cytotoxic / radiation therapy.
Contraindications:
- individual intolerance of Fluconazole components (sodium stearate, lactose monohydrate, colloidal silicon dioxide) Important: Parenteral tablets of iterfenadine, cisapride, astemizole, quinidine are not recommended;
- cardiomyopathy, renal / hepatic insufficiency, arrhythmia, bradycardia;
- pregnancy, lactation, elderly age (over 65 years).
Fluconazole for thrush - side effect
With the correct dosage and intake scheme, fluconazole does not cause serious complications and side effects. In 15% of patients, allergic reactions to the active substance (urticaria, erythema, rash), malfunctions in the functioning of the gastrointestinal tract are possible. Very rarely (1-2% of cases) are nausea, headache, dizziness, liver damage.
How to drink Fluconazole for thrush in women
The daily dose of the drug depends on the severity of the inflammation and the stage of the pathological process, therefore it is determined and, if necessary, adjusted only by the attending physician. Before the course of treatment, a microbiological examination is carried out, laboratory tests for the presence of dysbacteriosis and STDs. The acute course of urogenital thrush requires combination therapy: Fluconazole tablets + local remedies (suppositories, ointments, creams). For light forms of thrush, only one capsule of the drug (150 mg) is sufficient. The medicine should be swallowed whole, without chewing, squeezed with enough liquid. Treatment of chronic candidiasis is carried out according to the scheme: two-time administration of Fluconazole for three days (150 mg), the full course is 28 days. For the prevention of relapse - on the first day of the cycle, one capsule for 5-12 months. The recommended daily intake for children is 3 mg / kg of body weight, in the first 24 hours it is advisable to take 6 mg / kg per day. The duration of therapy should not exceed 14 days. For the prevention of thrush with antibiotic therapy, the dose is 50-300 mg once.
Fluconazole for men with thrush
In men in 45-50% of cases, infection with Candida fungus occurs during sexual intercourse. In the first stage, the disease manifests itself only by a mild burning sensation, as it progresses, the symptomatology deepens: there is hyperemia and swelling of the penis, scarlet spots of various shapes and sizes on the penis head, severe itching and burning in the perineum, abundant cheesy discharge with an unpleasant acidic odor. Running thrush can lead to the formation of cracks on the surface of the foreskin, sclerosis, fibrosis. The standard dosage of Fluconazole for treatment of candidiasis in men is 150 mg (single dose). Repeated reception of the drug - after 7 days. Therapy Fluconazole must be combined with the treatment of local effects - treat the genitals with antifungal creams / ointments.
Fluconazole for thrush: doctor's reviews
In the treatment of candidiasis, there are two main problems: self-medication attempts without a preliminary examination and later appeal to physicians. To make the correct diagnosis and appoint an adequate therapy can only specialist. Fluconazole for thrush is considered to be the most effective drug from the line of antimycotic drugs of systemic action. To cure an acute episode, one capsule of Fluconazole is sufficient. If episodes of candidiasis are repeated 3-5 times a year, a long course is necessary - every 7 days for 150 mg of Fluconazole for 6-7 months.